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9 thoughts on “C25 – Hord”
Hello Molly! Your presentation was great. Why exactly did you pick Wd40?
Hi Zoe! My group and I did not “pick” Wd40 as it was assigned to us as a gene within the Tetrahymena Thermophila genome to study.
Does the WD40 superfamily have other genes that are known to have direct effects on DNA repair?
Our gene specifically as a part of the WD40 superfamily isn’t necessarily known to have direct effects on DNA damage repair, as that is what we were trying to figure out throughout our research. All we know about the WD40 super family is that its genes are known to play a part in signal transduction as well as regulatory processes. As far as my group and I know, there aren’t any known genes within the WD40 superfamily that are known to play a part in DNA Damage Repair specifically, however, considering what is known about WD40, our hypothesis was that Wcop40 could play a role in DNA damage repair based off prior knowledge of the WD40 superfamily.
By deleting the Wcop40 in later experiments, what role would you be studying exactly? What would you specifically be looking for if that gene was not in play/being studied?
Yes, we would specifically be looking to clarify that it doesn’t play a role in the DNA Damage Repair pathway as our results show signs of possible error
What are double strand breaks?
Double Strand breaks are damage or breaks within both strands of DNA. In other words, it is when both strands of given DNA are chemically altered or damaged, in contrast to single strand breaks in which this damage only occurs in one strand of a given section of DNA.
Great presentation! I was wondering if there would be any drawbacks or limitations of using a drug that can help DNA repair. Because you mentioned that the drug can also reduce the affects of aging, are there any possible side effects of consistent use of DNA damage repair? There is an ongoing debate about the downsides of causing aging to stop.