Long term steps would include using data obtained from these experiments to provide additional insight on DNA damage repair pathways which could lead to new developments in science and medicine (ex. medications).
Good question! There are genes out there with a similar expression profile to Cory. However it should be noted that Cory hasn’t be widely researched and has no known homologs. Further research is warranted because of this in order to accurately determine this.
Though you used hydroxyurea to induce the DNA damage, do you believe or have you found sources that Cory would also experience upregulation regardless of how the DNA damage occurred?
Good question! While we only induced DNA damage in these experiments using hydroxyurea, I would assume that there would be an upregulation regardless of how the DNA damage occurred. However, the results from our experiment are limited and this idea would be interesting to test.
you talked about some of future steps in the short-term, but, what are some of the long term steps?
Long term steps would include using data obtained from these experiments to provide additional insight on DNA damage repair pathways which could lead to new developments in science and medicine (ex. medications).
Are there other genes that Cory’s expression is highly correlated with/regulated by that should be considered?
Are there other genes with activity very highly correlated to that of Cory or that regulate Cory that could be considered in relation?
Good question! There are genes out there with a similar expression profile to Cory. However it should be noted that Cory hasn’t be widely researched and has no known homologs. Further research is warranted because of this in order to accurately determine this.
Though you used hydroxyurea to induce the DNA damage, do you believe or have you found sources that Cory would also experience upregulation regardless of how the DNA damage occurred?
Good question! While we only induced DNA damage in these experiments using hydroxyurea, I would assume that there would be an upregulation regardless of how the DNA damage occurred. However, the results from our experiment are limited and this idea would be interesting to test.
What else do you know about Cory other than that it has a similar expression profile to Rad51 and that it is upregulated early in conjugation?
We know that it has no homologs or domains, no introns, no single peptide, and has no predicted locations, functions, or processes.