If you were to use an acid other than ellagic acid, would you want it to also be a similar one found in fruits and buts or would you rather test an acid with completely different properties?
Hey Kristina! I think if I didn’t use ellagic acid I would still have wanted to use a compound from a fruit/vegetable plant because I like the idea of using something that is easily accessible and possibly under-tested. With that, I would still want to make sure the compound has been found to have medicinal properties.
Thank you! Oddly enough, before ellagic acid we were considering platypus venom! We were interested in testing something that was “out there” and it happened to actually have medicinal properties.
Thank you! Oddly enough, we were planning to test platypus venom. We were interested in testing something that was “out there” and it happened to have medicinal properties.
In our research we did not find any research that specifically looked at the toxicity of our compound. That being said they also did not use a low of doses as we did therefore they may not have considered it as the studies never went past testing it on isolated bacteria. Thanks for your question!
We were definitely quite concerned about its toxicity, every week was simply preparing an even lower dose to test haha. With that, we are pretty confident that it isn’t a poison considering it is bacteriostatic, meaning it is preventing the growth of the bacteria as opposed to killing it, but there is always room for error of course. If our findings are correct and it does work this well at such low doses it would be very exciting!
In many studies we found ellagic acid was tested alongside a number of other acids. With that, we could definitely pull from one of those assuming it also had promising properties. The reason we chose ellagic acid, and the reason we think it worked well, is because it has been known to work against gram-negative bacteria. It is also a phenol antioxidant which can help break the cycle of the generation of new radicals which can help prevent a number of chronic illnesses. Thanks for your question!
If you were to use an acid other than ellagic acid, would you want it to also be a similar one found in fruits and buts or would you rather test an acid with completely different properties?
Hey Kristina! I think if I didn’t use ellagic acid I would still have wanted to use a compound from a fruit/vegetable plant because I like the idea of using something that is easily accessible and possibly under-tested. With that, I would still want to make sure the compound has been found to have medicinal properties.
Great work, what were some of the other options that you considered before deciding on ellagic acid for your experiment?
Thank you! Oddly enough, before ellagic acid we were considering platypus venom! We were interested in testing something that was “out there” and it happened to actually have medicinal properties.
Thank you! Oddly enough, we were planning to test platypus venom. We were interested in testing something that was “out there” and it happened to have medicinal properties.
Has any existing research been conducted on the toxicity of Ellagic Acid in vivo?
In our research we did not find any research that specifically looked at the toxicity of our compound. That being said they also did not use a low of doses as we did therefore they may not have considered it as the studies never went past testing it on isolated bacteria. Thanks for your question!
Do you think it is possible that your compound is more a poison instead of a drug? It is amazing to me that it still worked in such low doses!
We were definitely quite concerned about its toxicity, every week was simply preparing an even lower dose to test haha. With that, we are pretty confident that it isn’t a poison considering it is bacteriostatic, meaning it is preventing the growth of the bacteria as opposed to killing it, but there is always room for error of course. If our findings are correct and it does work this well at such low doses it would be very exciting!
Do you know if there are any other acids that you think would work for the experiment? Do you know what properties made it efficient?
In many studies we found ellagic acid was tested alongside a number of other acids. With that, we could definitely pull from one of those assuming it also had promising properties. The reason we chose ellagic acid, and the reason we think it worked well, is because it has been known to work against gram-negative bacteria. It is also a phenol antioxidant which can help break the cycle of the generation of new radicals which can help prevent a number of chronic illnesses. Thanks for your question!