In our future directions, we talked about testing just resveratrol and seeing its effects. I hypothesize we will expect similar results (i.e chemotherapeutic hit) because of how well the complex worked
In our further directions, we talked about testing just resveratrol with its respective dilutions. I hypothesize we would expect similar results (i.e chemotherapeutic hit) since the complex worked so well
Really great presentation! Do you think that the compound you tested on the fruit flies should be studied on organisms that are more similar to the human body? If so, what type of organism would this be?
Thanks, and yes I believe it should be tested on organisms similar to humans, like mice, in the future to see how it interacts in a body (how it is absorbed, digested, and excreted).
I know that radiation during cancer treatment can be inherently mutagenic itself, do you think that a combination of drugs including Resveratrol would also be effective at killing rapidly dividing cells or if it needs to be paired with radiation?
Because of how toxic the resveratrol was in combination with radiation (less than 7% survival for all trials), I believe it, in principle, would be effective in killing the rapidly dividing flies, but I’m not sure if it would be enough to be a statistically significant chemotherapeutic hit
Fascinating research! If you were to do further research on Resveratol, which model organism do you think would be the natural choice after the progress made with drosophila.
It’s not letting me reply to anyone so I will address them in individual comments
To Rachel: In our further directions, we talked about testing just resveratrol with its respective dilutions. I hypothesize we would expect similar results (i.e chemotherapeutic hit) since the complex worked so well
Would you study the effects of just Resveratrol as opposed to the complex in a similar manner as this and would you expect similar results?
In our future directions, we talked about testing just resveratrol and seeing its effects. I hypothesize we will expect similar results (i.e chemotherapeutic hit) because of how well the complex worked
In our further directions, we talked about testing just resveratrol with its respective dilutions. I hypothesize we would expect similar results (i.e chemotherapeutic hit) since the complex worked so well
Really great presentation! Do you think that the compound you tested on the fruit flies should be studied on organisms that are more similar to the human body? If so, what type of organism would this be?
Thanks, and yes I believe it should be tested on organisms similar to humans, like mice, in the future to see how it interacts in a body (how it is absorbed, digested, and excreted).
What are the advantages of continuing testing to see how low of a concentration you can get while it still being a hit?
A lower diltution dose means we can deliver a less toxic amount to a future patient, in turn decreasing potential side effects
I know that radiation during cancer treatment can be inherently mutagenic itself, do you think that a combination of drugs including Resveratrol would also be effective at killing rapidly dividing cells or if it needs to be paired with radiation?
Because of how toxic the resveratrol was in combination with radiation (less than 7% survival for all trials), I believe it, in principle, would be effective in killing the rapidly dividing flies, but I’m not sure if it would be enough to be a statistically significant chemotherapeutic hit
Fascinating research! If you were to do further research on Resveratol, which model organism do you think would be the natural choice after the progress made with drosophila.
Imagine I had typed a question mark instead of a period 😛
I probably would test in mice, so I can see how the drug interacts in a body
It’s not letting me reply to anyone so I will address them in individual comments
To Rachel: In our further directions, we talked about testing just resveratrol with its respective dilutions. I hypothesize we would expect similar results (i.e chemotherapeutic hit) since the complex worked so well
Actually never mind it is letting me reply now sorry
What differences between trans-Resveratol and Resveratol lead you to believe that testing them independently will yield different results?
I never said they would yield different results, but that by testing them individually, we can see how they independently impact the flies