10 thoughts on “D5C – McCormick

  1. I really enjoyed the presentation! One question I have is whether the treatment of the drug could possibly work without radiation, or is radiation necessary?

    1. Hello, I am glad you enjoyed my presentation! I do not think it would be as effective if used without irradiation because it causes DNA damage to the tumor cell, which is necessary to destroy it. That would be cool to test in the future though!

  2. Are you aware of any potential symptoms that could occur from the chemotherapy in the second experiment?

    1. Hello, unfortunately because we were only able to test one dilution, I do not know of any potential symptoms that could occur.

  3. Nice work! Are there any concerns about using fly larvae as model organisms? How well do you think the findings will reflect efficacy in other organisms?

    1. Thank you! One concern from using flies could be their level of irradiation. 2,500 RADS is a gigantic amount of radiation (typical radiation treatments in humans is less than 100 RADs) so if hypothetically this compound was approved to move further into clinical trials, the amount of radiation would have to be considered.

  4. Nice work! How well do you think the findings in larvae will reflect efficacy of the treatment in other organisms?

    1. Thank you! Since the larvae are representative of cancer cells, I am not entirely sure how it would be modeled to measure the survival rate of the cancer in another organism. I would hope the rates are similar because that means cancer is not being spread.

  5. beautiful presentation! what future experiments would you want to do to further research methiothepin maleate as a cancer treatment option?

    1. Thank you! I would definitely love to continue experiment two, the combination of colchicine and methiothepin maleate, with more serial dilutions to find other potential hits. I would also like to test if methiothepin maleate, without radiation, is an effective chemotherapeutic.

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