Korean red ginseng(KRG) may have only worked as an antimicrobial on E. coli and not salmonella because there may be a difference in the two bacterium’s’ drug uptake and retention. They may also have different sensitivities that may effect the efficacy of KRG as a antimicrobial on the different bacteria for instance E. coli may be more susceptible to the antimicrobial properties of KRG.
While the promising research referenced in the presentation did not specifically use salmonella they used bacteria that were closely related for example E. coli is also gram-negative and in the family as salmonella. The literature used does not contain anything about using Korean Red Ginseng, KRG, as a potential antimicrobial against salmonella, nor could I find anything that researched this specifically. However the research referenced did show that KRG worked as a bactericidal against E. coli.
Because there was a lot of research that showed Korean Red Ginseng working as an effective antimicrobial against gram-negative bacteria, like E. coli, our current theory is that there are antimicrobial properties in KRG but they are being overshadowed by the nutrients in the KRG supplement.
What do think could be a reason why the ginseng worked with e. coli but did not with salmonella?
Korean red ginseng(KRG) may have only worked as an antimicrobial on E. coli and not salmonella because there may be a difference in the two bacterium’s’ drug uptake and retention. They may also have different sensitivities that may effect the efficacy of KRG as a antimicrobial on the different bacteria for instance E. coli may be more susceptible to the antimicrobial properties of KRG.
In the promising research that suggested the ginseng worked on Salmonella did they run a similar experiment which got different results?
While the promising research referenced in the presentation did not specifically use salmonella they used bacteria that were closely related for example E. coli is also gram-negative and in the family as salmonella. The literature used does not contain anything about using Korean Red Ginseng, KRG, as a potential antimicrobial against salmonella, nor could I find anything that researched this specifically. However the research referenced did show that KRG worked as a bactericidal against E. coli.
In addition to it being marketed as a supplement, what made you think that the compound may promote bacterial growth?
Because there was a lot of research that showed Korean Red Ginseng working as an effective antimicrobial against gram-negative bacteria, like E. coli, our current theory is that there are antimicrobial properties in KRG but they are being overshadowed by the nutrients in the KRG supplement.
Is it possible that ginseng did not infect salmonella due to the conditions of the experiments rather than the bacterial strain?
This could totally be possible. The media, the solvent, may have interfered with the uptake of our compound and could have effected the results.
This could be a possibility. The media, or the solvent, used could have interfered with the salmonella’s drug uptake.