15 thoughts on “D70 – Attah Amoah

  1. It’s interesting that in your max dose experiment, percent survival increased with radiation. Do you think your compound could have a radiation protection effect?

    1. Although our percent survival increased it wasn’t 2 SD above our negative control (which is what we determined as our parameter for classifying radiation protectors.

    2. It wasn’t classified as a radiation protector because percent survival wasn’t 2 SD above our negative control (what was classified as a rad protector).

  2. Great presentation! How would the experiment change if you tested fly cells with mutated E flux pumps? I’m not sure what E flux pumps are.

    1. Thank you! Some studies have shown that NSAIDs promote cell drug toxicity so I assume our percent survival would decrease.

  3. Great presentation! You mentioned the fairly high variability of the amount of larvae per vial. Is there any way you can think to lower this variability to be able to produce more precise results?

    1. Thank you!! Yes actually our goal was to get approximately 50 larvae per vial increasing our population size and making out data statistically significant. I good way to overcome this will be to ensure that we transfer a significant amount of larvae into our vials and also by making multiple vials.

  4. Great presentation! You mentioned the high variability of the amount of larvae per vial. How would you reduce this variability to be able to get more precise results?

  5. Could you explain a bit more in detail about what the “hits” in your results mean?

    1. In our results a “hit” means our percent survival was 2 SD below our negative control (a compound we know isn’t a chemotherapy). Classified hits mean our compound could be a potential combinational chemotherapy with radiation.

  6. Hey Amoah great poster and presentation. When you said in future directions you would repeat the experiment more times, would having the exact amount of larva in each vial change the results to be more conclusive?

    1. Yes it will!! it will also increase our population size and make our data statistically significant.

  7. Hey Attah Amoah that was a great poster and presentation. You referenced in future directions you would conduct the experiment more times to further results. Would ensuring the precise amount of larva in the vials change the results to be more conclusive? If not, why would repeating these steps aid in further research?

    1. Having only one trial for any experiment leaves room for errors. Having multiple trials makes your results more conclusive!!.

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