View the poster here. Share this:Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Like this:Like Loading...
11 thoughts on “D72 – Reese”
Maybe I missed the explanation, but what exactly is a “hit” in the context of your research? You mention it a few times in the Methods and Results sections.
Maybe I missed the explanation, but what exactly is a “hit” in the context of your research? You mention it a few times in the Methods and results section.
Hi, thank you for your question! A “hit” in the context our research was an absorbance value of the compound furamidine treated with bacteria that was lower than 2 standard deviations from the mean of the negative control which shows that the compound successfully killed S. Typhimurium.
Why would injecting the compound into an organism differ from the experiments you ran? What other factors does this allow you to test or control for?
Hi Sarah thank you for asking! Injecting the compound into an organism could allow us to determine the solubility and stability of the compound and if the drug would leave the liver. This could help us obtain more information on the toxicity of the compound as a drug because liver cells are very likely to experience toxicity.
What future direction do you think is the most important?
Thank you so much for your question! I think the most important future direction would be to retest the compound to confirm its efficacy. Since we obtained strong results and every concentration of the compound tested did kill the growth of the bacteria, retesting with more replicates and increasing the number of doses could help us to see if there is more variability in our results.
Why do you think it is important to conduct further testing to understand the effects?
Hi Brain thank you for asking! I think it is important to conduct further research to understand the effects because we only performed this experiment once, so it could be helpful to obtain more data and results on its effects on bacteria. I also think it would be important to administer the compound into animals to see how this compound may act similarly or different in an animal model.
Do you think furamidine would have adverse effects in humans?
Hi Elizabeth! cannot say for sure but based on our results we found furamidine to work more as a drug that kills the bacteria rather than just working as a poison and killing the bacteria, so based on that I would predict that it will work similarly in humans. But we would need to continue research to be able to determine the effects of furamidine on humans.