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Is there any evidence to suggest that MGO is toxic at the concentrations in which you observe bactericidal effects? Loading... Reply
i believe not but MGO can be toxic to neuroblastoma cells in a dose dependent manner above concentration of 0.15 mM, and also has a LD50 of 1.25mM Loading... Reply
its a highly reactive dicarbonyl compound. And is a precursor of advanced glycation end-products (AGEs) which have been linked to many pathologies including diabetes and more. Loading... Reply
Is there any evidence to suggest that MGO is toxic at the concentrations in which you observe bactericidal effects?
i believe not but MGO can be toxic to neuroblastoma cells in a dose dependent manner above concentration of 0.15 mM, and also has a LD50 of 1.25mM
What about MGO’s structure may cause it to be so toxic?
its a highly reactive dicarbonyl compound. And is a precursor of advanced glycation end-products (AGEs) which have been linked to many pathologies including diabetes and more.