Our testing likly wont be helpful towards tuberculosis immediatly. This was an effort to expand our archive on phages; however, an expanded archive may in turn help with the promising feild of phage therapy. Phage therapy is the use of bacteriophage in targeting harmful bacteria/pathogens. The Journal of Infectious Diseases had published an article in 2002 examining a delivery method to introduce the phage TM4 into sites infected with the bacteria Mycobacterium avium and Mycobacterium tuberculosis, both of which are related to tuberculosis. This would allow TM4 to reach the infected sites and begin distroying the harmful bacteria colonies. If you’d like to read more the article I’m refering to is titled “Killing of Mycobacterium avium and Mycobacterium tuberculosis by a Mycobacteriophage Delivered by a Nonvirulent Mycobacterium: A Model for Phage Therapy of Intracellular Bacterial Pathogens” by Lawrence Broxmeyer et al. Thank you for the great question.
do you think testing this on tuberculosis would be helpful and why?
Our testing likly wont be helpful towards tuberculosis immediatly. This was an effort to expand our archive on phages; however, an expanded archive may in turn help with the promising feild of phage therapy. Phage therapy is the use of bacteriophage in targeting harmful bacteria/pathogens. The Journal of Infectious Diseases had published an article in 2002 examining a delivery method to introduce the phage TM4 into sites infected with the bacteria Mycobacterium avium and Mycobacterium tuberculosis, both of which are related to tuberculosis. This would allow TM4 to reach the infected sites and begin distroying the harmful bacteria colonies. If you’d like to read more the article I’m refering to is titled “Killing of Mycobacterium avium and Mycobacterium tuberculosis by a Mycobacteriophage Delivered by a Nonvirulent Mycobacterium: A Model for Phage Therapy of Intracellular Bacterial Pathogens” by Lawrence Broxmeyer et al. Thank you for the great question.
How did you isolate your phage?
How do phages perform cell lysis?
Why did you choose the phage clusters that you utilized in this experiment? Good job!
Why are these phage clusters the ones that you decided were most important? How did you find your primers?