Hello! Great question. Because my group ultimately concluded that Wd40 gene in T. thermophila most likely does not take part in DNA replication repair, the best option would be to shift the focus away from DNA damage repair and perhaps study how protein-protein interactions occur in relation to the WD40 Superfamily domain. Ultimately, we could compare known functions of the WD40 superfamily domain (protein) to the wd40 gene itself.
Based on introduction, abstract and figure and legend drafts I peer reviewed throughout the semester, I did not come across any gene of interest studied aiding in DNA damage repair in T. thermophila. With that being said, I am sure there were a few groups who did identify the positive result, ultimately aiding in DNA damage repair. Regardless of the results obtained, I think that further testing should occur in order to collect the most accurate data.
How would you go about finding the exact function of the gene if given more time?
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Hello! Great question. Because my group ultimately concluded that Wd40 gene in T. thermophila most likely does not take part in DNA replication repair, the best option would be to shift the focus away from DNA damage repair and perhaps study how protein-protein interactions occur in relation to the WD40 Superfamily domain. Ultimately, we could compare known functions of the WD40 superfamily domain (protein) to the wd40 gene itself.
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Do you have any hypothesized genes that you believe were responsible for the DNA damage response?
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Based on introduction, abstract and figure and legend drafts I peer reviewed throughout the semester, I did not come across any gene of interest studied aiding in DNA damage repair in T. thermophila. With that being said, I am sure there were a few groups who did identify the positive result, ultimately aiding in DNA damage repair. Regardless of the results obtained, I think that further testing should occur in order to collect the most accurate data.
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