If I’m understanding your question correctly, your asking what Cory is and how it pertains to DNA Damage in our experiment? If so, DNA damage was induced in the model organism T. therm with a chemical called hydroxyurea. After DNA damage to the organism, we tested it’s genetic expression of a gene already in its genome, Cory, to see if this genes expression increased from the damage. If it had, than we would say that it may play a role in DNA repair.
Awesome job! Since the model organism is unicellular, how do we know that the results of your research are applicable to multicellular organisms? Is this gene found in most organisms?
Good question, so despite be unicellular, T. therm is a good model organism for the DNA repair pathway with relevancy to humans (multicellular) because it shares a lot of conserved cellular processes across eukaryotes, including many shared processes with humans. I got this fact from a paper titled “Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote” if your interested.
Were you testing something that can prevent/halt DNA damage or to amplify/make it easier to view DNA damage? I was a little bit confused.
LikeLike
If I’m understanding your question correctly, your asking what Cory is and how it pertains to DNA Damage in our experiment? If so, DNA damage was induced in the model organism T. therm with a chemical called hydroxyurea. After DNA damage to the organism, we tested it’s genetic expression of a gene already in its genome, Cory, to see if this genes expression increased from the damage. If it had, than we would say that it may play a role in DNA repair.
LikeLike
Awesome job! Since the model organism is unicellular, how do we know that the results of your research are applicable to multicellular organisms? Is this gene found in most organisms?
LikeLike
Good question, so despite be unicellular, T. therm is a good model organism for the DNA repair pathway with relevancy to humans (multicellular) because it shares a lot of conserved cellular processes across eukaryotes, including many shared processes with humans. I got this fact from a paper titled “Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote” if your interested.
LikeLike