How was procyanidin B1 chosen to be the subject of your research? Did all groups in drug discovery work with Cornelian Cherry proanthocyanidins or was this unique to your research?
We chose the Cornelian cherry because it’s a prominent remedy in Eastern medicine, and during our research we discovered that it has many compounds with antimicrobial properties. Each group chose a compound based off of their own research, so it was just my group that researched the Cornelian cherry/procyanidin B1.
Even though these results did not show antimicrobial properties of procyanidin B1, there are other ways that we could test the compound such as with antimicrobial peptides.
Our compound is not necessarily growth-promoting, but in order to compare it to other compounds that are also found in Cornelian cherries we could retest procyanidin B1 and test other compounds, all at the same concentration, and compare results. Sorry if that wasn’t a good response I might’ve misunderstood your question.
Adding antimicrobial peptides to our compound and then testing it against the bacteria would allow the compound to enter the bacterial cell more easily (these peptides poke holes in the membrane) so that we can examine how procyanidin B1 affects intracellular mechanisms.
Probiotics cause bacterial growth so they would not help to fight bacterial infections, but probiotics have other uses so it is important to know if procyanidin B1 does have probiotic properties.
curesymposium.org 
How was procyanidin B1 chosen to be the subject of your research? Did all groups in drug discovery work with Cornelian Cherry proanthocyanidins or was this unique to your research?
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We chose the Cornelian cherry because it’s a prominent remedy in Eastern medicine, and during our research we discovered that it has many compounds with antimicrobial properties. Each group chose a compound based off of their own research, so it was just my group that researched the Cornelian cherry/procyanidin B1.
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What are some implications of the findings of your research now? Is there anything that can be contributed considering your findings came up negative?
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Even though these results did not show antimicrobial properties of procyanidin B1, there are other ways that we could test the compound such as with antimicrobial peptides.
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How would you conduct a comparative experiment on other growth-promoting compounds?
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Our compound is not necessarily growth-promoting, but in order to compare it to other compounds that are also found in Cornelian cherries we could retest procyanidin B1 and test other compounds, all at the same concentration, and compare results. Sorry if that wasn’t a good response I might’ve misunderstood your question.
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How would antimicrobial peptides reduce bacteria growth?
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Adding antimicrobial peptides to our compound and then testing it against the bacteria would allow the compound to enter the bacterial cell more easily (these peptides poke holes in the membrane) so that we can examine how procyanidin B1 affects intracellular mechanisms.
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Why would a probiotic be beneficial to fighting bacterial infection?
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Probiotics cause bacterial growth so they would not help to fight bacterial infections, but probiotics have other uses so it is important to know if procyanidin B1 does have probiotic properties.
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