Cinnamic acid has the ability to inhibit the ischorismatase enzyme which is contained in Salmonella. This enzyme is also present in other bacteria but Salmonella Typhimurium was the chosen model bacteria for this experiment because of its safe nature in testing around humans.
I am unable to definitively answer this without further testing on other strains of Salmonella. My hypothesis would say that the effects would be similar between differnt strains.
You mention that cinnamic acid has had success in fighting E.Coli infections, and since Salmonella is also gram+, it may find similar results. How are there other shared characteristics between E.Coli and Salmonella that may help support this?
Along with being gram negative both e. Coli and Salmonella inhabit the intestines when they infect the body. The shared similar environments is another large promising similarity between the two bacterias.
Along with being gram negative both e. Coli and Salmonella inhabit the intestines when they infect the body. The shared similar environments is another large promising similarity between the two bacteria’s.
I first would account our inconclusive results to random error that may of occurred in our procedure and we were only able to repeat our experiment twice which may noy be enough to eliminate error form our data. We also only looked for antimicrobial activity in physiologically relevant concentrations of Cinnamic acid of 10uM and under. We did accidentally plate concentrations higher than this and there were many “hits” present in these high concentrations which could be to what these literature findings are addressing.
I first would account our inconclusive results to random error that may of occurred in our procedure and we were only able to repeat our experiment twice which may noy be enough to eliminate error form our data. We also only looked for antimicrobial activity in physiologically relevant concentrations of Cinnamic acid of 10uM and under. We did accidentally plate concentration higher than this and there were many “hits” present in these high concentrations which could be to what these literature findings are addressing.
curesymposium.org 
How does cinnamic acid correlate to salmonella?
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Cinnamic acid has the ability to inhibit the ischorismatase enzyme which is contained in Salmonella. This enzyme is also present in other bacteria but Salmonella Typhimurium was the chosen model bacteria for this experiment because of its safe nature in testing around humans.
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Does cinnamic acid have effects on all strands of salmonella or only the ones tested?
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I am unable to definitively answer this without further testing on other strains of Salmonella. My hypothesis would say that the effects would be similar between differnt strains.
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You mention that cinnamic acid has had success in fighting E.Coli infections, and since Salmonella is also gram+, it may find similar results. How are there other shared characteristics between E.Coli and Salmonella that may help support this?
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Along with being gram negative both e. Coli and Salmonella inhabit the intestines when they infect the body. The shared similar environments is another large promising similarity between the two bacterias.
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Along with being gram negative both e. Coli and Salmonella inhabit the intestines when they infect the body. The shared similar environments is another large promising similarity between the two bacteria’s.
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Why do you think that the literature results for the Cinnamic Acid on bacteria are different than the results that were produced in this experiment?
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I first would account our inconclusive results to random error that may of occurred in our procedure and we were only able to repeat our experiment twice which may noy be enough to eliminate error form our data. We also only looked for antimicrobial activity in physiologically relevant concentrations of Cinnamic acid of 10uM and under. We did accidentally plate concentrations higher than this and there were many “hits” present in these high concentrations which could be to what these literature findings are addressing.
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I first would account our inconclusive results to random error that may of occurred in our procedure and we were only able to repeat our experiment twice which may noy be enough to eliminate error form our data. We also only looked for antimicrobial activity in physiologically relevant concentrations of Cinnamic acid of 10uM and under. We did accidentally plate concentration higher than this and there were many “hits” present in these high concentrations which could be to what these literature findings are addressing.
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