8 thoughts on “D74-Knutson

    1. Great question. Since this information was from another source, I am not completely familiar with the mechanisms by which the membrane was compromised. My best guess would be that 4HBITC ruptures the membrane in some way, and without the semipermeable barrier the cell integrity as a whole is endangered.

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    1. Yes. If a drug developed from this compound successfully kills Salmonella Typhi, it is guaranteed to be successful against Salmonella Typhimurium, since they share the same structure. It may also kill similarly gram-negative bacterium since they share structural similarities, but testing would be required to verify this.

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    1. We want to repeat the experiments to make sure the results were not dependent on human error or other uncontrolled variables, especially our second dilution series that had mixed results.

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