What do you think would be the difference in the effects of Mycobacteriophage in Mice with Communicable diseases vs Noncommunicable diseases, if there are any?
According to recent studies on the impact of chemical exposure on bacteriophage, I would expect its efficacy to be substantially greater in communicable diseases since body temperature does not deviate the bodies natural processes of homeostasis as much as noncommunicable diseases, such as cancer that can metastasize and impact multiple regions throughout the body on the cellular level.
Would there be any steps you would be interested in taking before beginning animal trials? Were you looking at testing the phage you isolated for this research or with the phage from the paper?
Hi! I would like to test a phage that is specific to a bacteria commonly found in human hosts that aren’t seriously pathogenic like tuberculosis, since the bacteria utilized in this experiment is not typically found in human or animal hosts! I would most likely perform similar procedures outlined in this poster to begin animal trials and ensure that a hyperimmune response will not occur by adding protective proteins to the phages anatomy!
I saw that in your future experiments, you mentioned that your experiment can be continued in mice. Is there any possibility of being animal free in this experiment?
Hi! There is definitely a possibility of being animal free, it would just yield less similar results to a human host compared to invivo experimentation!
curesymposium.org 
What do you think would be the difference in the effects of Mycobacteriophage in Mice with Communicable diseases vs Noncommunicable diseases, if there are any?
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What do you think would be the difference in the effect of Mycobacteriophage on communicable vs noncommunicable diseases in mice, if there were any?
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According to recent studies on the impact of chemical exposure on bacteriophage, I would expect its efficacy to be substantially greater in communicable diseases since body temperature does not deviate the bodies natural processes of homeostasis as much as noncommunicable diseases, such as cancer that can metastasize and impact multiple regions throughout the body on the cellular level.
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Would there be any steps you would be interested in taking before beginning animal trials? Were you looking at testing the phage you isolated for this research or with the phage from the paper?
LikeLike
Hi! I would like to test a phage that is specific to a bacteria commonly found in human hosts that aren’t seriously pathogenic like tuberculosis, since the bacteria utilized in this experiment is not typically found in human or animal hosts! I would most likely perform similar procedures outlined in this poster to begin animal trials and ensure that a hyperimmune response will not occur by adding protective proteins to the phages anatomy!
LikeLike
I saw that in your future experiments, you mentioned that your experiment can be continued in mice. Is there any possibility of being animal free in this experiment?
LikeLike
Hi! There is definitely a possibility of being animal free, it would just yield less similar results to a human host compared to invivo experimentation!
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