The restriction digest is used to compare our phage’s genome to other phages in the database. The restriction enzymes cut out specific DNA sequences and phages with similar cuts have similar genomes. This is used to find which cluster the phage is in.
The clusters are similar to species in animals and plants. Phages in the same cluster have similar genomes. Phages in the same cluster have similar traits and might be able to treat similar antibiotic resistant infections as one another. Overall knowing the cluster is just a way to categorize each phage in the database to make it more organized.
The clusters are used to categorize each phage, similar to species in plants and animals. Knowing the cluster allows us to know which phages ours is similar to and allows the database of discovered phages to be more organized.
Hi Andrew!
Really well done presentation. I was wondering why you carried out a restriction digest?
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The restriction digest is used to compare our phage’s genome to other phages in the database. The restriction enzymes cut out specific DNA sequences and phages with similar cuts have similar genomes. This is used to find which cluster the phage is in.
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Hi! I was wondering what the impact of finding that your phage belongs to cluster N means for antibiotic resistance or for your phage in general?
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The clusters are similar to species in animals and plants. Phages in the same cluster have similar genomes. Phages in the same cluster have similar traits and might be able to treat similar antibiotic resistant infections as one another. Overall knowing the cluster is just a way to categorize each phage in the database to make it more organized.
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What is the importance of Mugsy belonging to clusters A5 or N?
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The clusters are used to categorize each phage, similar to species in plants and animals. Knowing the cluster allows us to know which phages ours is similar to and allows the database of discovered phages to be more organized.
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