Hi Lindsy! Yes, the shape of the tails determine which host cells they can infect. The tail length also indicates the length of the gene which the phage possesses.
Awesome job! What types of diseases would mycobacteriophages treat? Have mycobacteriophages been more successful in treatment than other antimicrobials?
Hi Shay! The temperate phage can be used in research once the integrase and repressor gene are removed. This will allow the phage to undergo a complete lytic life cycle and fully lyse its host bacterial cells.
Hi Shay! The phage can be used in research once the integrase and repressor gene are removed. This will allow the phage to undergo a complete lytic life cycle and fully lyse the host bacterial cells.
Can you clarify what it means to be a part of K1 or N cluster, and how restriction enzyme digest shows this? Are there combinations of restriction enzymes that are exclusive to specific clusters? Great presentation and love the name “Baked potato”!
Do the size and shape of the tails change the way that the phage function?
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Hi Lindsy! Yes, the shape of the tails determine which host cells they can infect. The tail length also indicates the length of the gene which the phage possesses.
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What could be a possible use for your phage if more research could be conducted?
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Hi Elle! If further research is conducted, our phage could potentially be used a cure to or treatment of an antibiotic-resistant bacterial infection.
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Awesome job! What types of diseases would mycobacteriophages treat? Have mycobacteriophages been more successful in treatment than other antimicrobials?
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Thank you Barbara! Mycobacteriophages have been used to treat infections such as M. tuberculosis and M. abscessus.
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Thank you Barbara! Mycobacteriophages have been used to treat Mycobacterium infections such as M. tuberculosis and M. abscessus.
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Since your phage is a temperate, can it be used in research if it is mixed with other phages?
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Hi Shay! The temperate phage can be used in research once the integrase and repressor gene are removed. This will allow the phage to undergo a complete lytic life cycle and fully lyse its host bacterial cells.
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Hi Shay! The phage can be used in research once the integrase and repressor gene are removed. This will allow the phage to undergo a complete lytic life cycle and fully lyse the host bacterial cells.
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Can you clarify what it means to be a part of K1 or N cluster, and how restriction enzyme digest shows this? Are there combinations of restriction enzymes that are exclusive to specific clusters? Great presentation and love the name “Baked potato”!
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