Great poster. Since your phage is temperate it cannot always be used for phage therapy but on the off chance, it was how would it be used? Would it be changed to lytic?
Unfortunately a phage can’t be changed from temperate from lytic by any means we currently know of, so using other phages would be better for phage therapy.
Well, first of all, phage therapy currently hasn’t been tested enough for widespread use. It can also be expensive to engineer/find a phage that’ll kill the bacterial strain infecting a patient due to how incredibly specific phages are about their targets. “Cocktails” of multiple phages have shown to be promising but again, we just don’t have the research for widespread use yet.
Great poster. Since your phage is temperate it cannot always be used for phage therapy but on the off chance, it was how would it be used? Would it be changed to lytic?
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Unfortunately a phage can’t be changed from temperate from lytic by any means we currently know of, so using other phages would be better for phage therapy.
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Are you aware of any limitations regarding phage therapy, and if those could be the reason why it’s not so wildly used?
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Well, first of all, phage therapy currently hasn’t been tested enough for widespread use. It can also be expensive to engineer/find a phage that’ll kill the bacterial strain infecting a patient due to how incredibly specific phages are about their targets. “Cocktails” of multiple phages have shown to be promising but again, we just don’t have the research for widespread use yet.
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