Hi Gina, thank you for the question. We compared the gene expression map of Wd40 and another known gene that is involved in DNA damage response pathway, and the patterns were alike. This helped us came up the hypothesis.
Hi Emmett, thank you! If DNA damage occurred, there will have more gene expression. So on the gel, we could see a brighter band. Which means, when the band is brighter, that means DNA damage occurred.
Hi Aedan, thank you for the question! This is really a good question, however, because we really know not much about Wd40, more experiments and research will be needed to answer this. Thus, I don’t have the answer to the question.
Hi Drew, thank you! Wd40 gene can also be found in other species, thus technically we can use other cells for experiment. However, since T. Thermophilia is more easier to work with as a model organism.
Hi! What led you to come up with your hypothesis that Wd40 would cause this phenomenon?
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Hi Gina, thank you for the question. We compared the gene expression map of Wd40 and another known gene that is involved in DNA damage response pathway, and the patterns were alike. This helped us came up the hypothesis.
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Where is the Wd40 gene commonly found?
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Are there specific types of cancer that a treatment like this would be more effective in preventing?
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Hello, great poster and video! I’m a bit confused on how you are able to tell that the DNA bands are damaged. How exactly can you tell?
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Hi Emmett, thank you! If DNA damage occurred, there will have more gene expression. So on the gel, we could see a brighter band. Which means, when the band is brighter, that means DNA damage occurred.
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Is there a specific type of cancer that this treatment would be more effective in preventing?
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Do you know if there are any side effects from removing the Wd40 gene?
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Hi Aedan, thank you for the question! This is really a good question, however, because we really know not much about Wd40, more experiments and research will be needed to answer this. Thus, I don’t have the answer to the question.
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Great presentation! Could you test the effects of the Wd40 gene on other cells or is it very specific to T. Thermophilia?
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Hi Drew, thank you! Wd40 gene can also be found in other species, thus technically we can use other cells for experiment. However, since T. Thermophilia is more easier to work with as a model organism.
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