10uM is the usual standard maximum dose of most compounds that the human body can handle without toxicity however as one of our future direction states further research could show that a higher dosage is needed.
It’s hard to say as for the fact that you would need to also determine the highest dosage that the compound can be without also being toxic to human cells which could be tested through a therapeutic index.
Because there are several future directions listed, which one of those would you prioritize to complete that would aid the most in your research?
I believe testing different active compounds in piper guinese in combination with linalool would be the most promising direction.
Was there a reason that you chose 10 micromolar as the initial dose? Previous studies that support this possibly?
10uM is the usual standard maximum dose of most compounds that the human body can handle without toxicity however as one of our future direction states further research could show that a higher dosage is needed.
In the future, how high of a dose would you use in order to see further bacterial death?
It’s hard to say as for the fact that you would need to also determine the highest dosage that the compound can be without also being toxic to human cells which could be tested through a therapeutic index.