So you mentioned that you choice vidatox, because it had previously been used as a cancer treatment, but your results showed that vidatox was not good for stopping bacteria growth in salmonella typhi. In researching your compound did you find any other cases were vidatox was shown to be effective against certain other types of bacteria as an antibiotic that made you want to choice it for this experiment?
Great question! There was no research done in regards to VIdatox and bacteria. However, during our initial research, we found that Vidatox targets fast growing cells and we speculated that this “targeting” would be applicable to bacteria.
Why would you test other simmilar compounds to Vidatox if you suppose that they won’t also work? Since they’re simmilar, why won’t you just consider testing your compound in different ways?
You are absolutely right! We would want to test both similar compounds to solidify our conclusions on the effect of Vidatox as well as testing the compound in vivo instead of the 96-well plate.
You mentioned the trend in figure 3 despite none of the wells presenting hits. I was wondering if you had any thoughts on what brought about that trend and what it might represent?
That is a tricky question. While Vidatox did not present evidence that it is an antibiotic, there us still a relationship between the bacteria’s survival and its exposure to the compound.
Hello, very good presentation! You mentioned that vidatox was not successful in stopping bacteria growth in salmonella typhi, why do you think that is and would you consider testing it in another way that might be successful?
While I am not sure how Vidatox directly interacts with out salmonella, we would like to test our compound in vivo as it has shown to increase white blood cell count.
So you mentioned that you choice vidatox, because it had previously been used as a cancer treatment, but your results showed that vidatox was not good for stopping bacteria growth in salmonella typhi. In researching your compound did you find any other cases were vidatox was shown to be effective against certain other types of bacteria as an antibiotic that made you want to choice it for this experiment?
Great question! There was no research done in regards to VIdatox and bacteria. However, during our initial research, we found that Vidatox targets fast growing cells and we speculated that this “targeting” would be applicable to bacteria.
Why would you test other simmilar compounds to Vidatox if you suppose that they won’t also work? Since they’re simmilar, why won’t you just consider testing your compound in different ways?
You are absolutely right! We would want to test both similar compounds to solidify our conclusions on the effect of Vidatox as well as testing the compound in vivo instead of the 96-well plate.
You mentioned the trend in figure 3 despite none of the wells presenting hits. I was wondering if you had any thoughts on what brought about that trend and what it might represent?
That is a tricky question. While Vidatox did not present evidence that it is an antibiotic, there us still a relationship between the bacteria’s survival and its exposure to the compound.
Hello, very good presentation! You mentioned that vidatox was not successful in stopping bacteria growth in salmonella typhi, why do you think that is and would you consider testing it in another way that might be successful?
While I am not sure how Vidatox directly interacts with out salmonella, we would like to test our compound in vivo as it has shown to increase white blood cell count.