Would this drug be safe for chemotherapy patients? You mention the possible use for chemotherapy patients but you also mention the possibility of the drug being poisonous.
Vidatox would have to be proven to be safe when coming into contact with human cells in order to be used by anyone more so for chemotherapy patients. That would mean it would have to undergo testing that’s farther down the line in drug development. However, with the tests conducted by my partner and I we’ve shown that it could be a suitable candidate to continue testing. The possibility comes from peptides in certain venoms booting the immune systems of people who take them, and chemotherapy patients have lowered immune systems due to their treatments. So if those peptides are found in Vidatox and it gets FDA approval, there is a chance it can be used as an alternative antibiotic for chemotherapy patients.
To be honest, the possibility of Vidatox becoming an antibiotic at all is very slim. The last new antibiotic to be discovered was in 1987 during the “Golden Age” of antibiotics. Since then, there have only been repurposed antibiotics of existing ones to come out. The experiments performed on Vidatox in this lab are only the tip of the iceberg when it comes to drug development. However, Vidatox does show characteristics of what could potentially become an antibiotic, so if it is chosen for continued testing, it could show promise for becoming a novel antibiotic.
I wanted to start off by saing this is an awesome poster and presentation. It showed you have an extensive knowledge of not only the research you did but the background into the field. I did have a question I wanted to ask. You stated that you tested a chemical for antimicrobial useage because of its useage in effectively bypassing a pump used in tumors. Do you think there may be a link between antibiotics and tumor pumps?
Hi Cristian, thank you for that and your great question!
I do think that there is a link between antibiotics and tumor pumps because many tumors caused by cancer are multidrug resistant. The main way these tumors achieve that resistance it by the use of transporters, most commonly efflux pumps. Bacteria, like salmonella, also use efflux pumps to remove drugs from the cell which is how they become drug resistant. Since antibiotics are sometimes developed to bypass these efflux pumps then there is the possibility they could be used for tumors.
Would this drug be safe for chemotherapy patients? You mention the possible use for chemotherapy patients but you also mention the possibility of the drug being poisonous.
Hi Ethan, thanks for your question!
Vidatox would have to be proven to be safe when coming into contact with human cells in order to be used by anyone more so for chemotherapy patients. That would mean it would have to undergo testing that’s farther down the line in drug development. However, with the tests conducted by my partner and I we’ve shown that it could be a suitable candidate to continue testing. The possibility comes from peptides in certain venoms booting the immune systems of people who take them, and chemotherapy patients have lowered immune systems due to their treatments. So if those peptides are found in Vidatox and it gets FDA approval, there is a chance it can be used as an alternative antibiotic for chemotherapy patients.
How plausible is it that the use of Vidatox could become a common antibiotic in modern everyday use?
Hi Ruby, thank you for the question!
To be honest, the possibility of Vidatox becoming an antibiotic at all is very slim. The last new antibiotic to be discovered was in 1987 during the “Golden Age” of antibiotics. Since then, there have only been repurposed antibiotics of existing ones to come out. The experiments performed on Vidatox in this lab are only the tip of the iceberg when it comes to drug development. However, Vidatox does show characteristics of what could potentially become an antibiotic, so if it is chosen for continued testing, it could show promise for becoming a novel antibiotic.
Hello Sebastian Vargas,
I wanted to start off by saing this is an awesome poster and presentation. It showed you have an extensive knowledge of not only the research you did but the background into the field. I did have a question I wanted to ask. You stated that you tested a chemical for antimicrobial useage because of its useage in effectively bypassing a pump used in tumors. Do you think there may be a link between antibiotics and tumor pumps?
Look forward to hearing form you!
Cristian
Hi Cristian, thank you for that and your great question!
I do think that there is a link between antibiotics and tumor pumps because many tumors caused by cancer are multidrug resistant. The main way these tumors achieve that resistance it by the use of transporters, most commonly efflux pumps. Bacteria, like salmonella, also use efflux pumps to remove drugs from the cell which is how they become drug resistant. Since antibiotics are sometimes developed to bypass these efflux pumps then there is the possibility they could be used for tumors.