You say the solution to your original problem is to make more and stronger antibiotics. But does this solve the problem? Or will the bacteria only grow and adapt to the new antibiotic?
The problem of antibiotic resistance will always be a problem. Bacteria will always evolve to become resistant to antibiotics. This is why we need to continue to develop new types of antibiotics.
It is hard to say because our results came back so skewed. Due to that, it would not be accurate to say how the compound would be preform in vivo testing.
Mice would be the best option to test L-DilodoTyrosine. The reason is because Salmonella Typhi causes a similar response in mice that Salmonella Typhimurium causes in humans.
Stronger antibiotics are more aggressive towards the bacteria. Therefore the bacteria would have to have a very high resistance to that antibiotic. The best way to visualize this is with the video Aiden played in her presentation.
You say the solution to your original problem is to make more and stronger antibiotics. But does this solve the problem? Or will the bacteria only grow and adapt to the new antibiotic?
The problem of antibiotic resistance will always be a problem. Bacteria will always evolve to become resistant to antibiotics. This is why we need to continue to develop new types of antibiotics.
What results would you expect from the additional future experiment of testing in vivo?
It is hard to say because our results came back so skewed. Due to that, it would not be accurate to say how the compound would be preform in vivo testing.
In the future, what do you suggest L-Dilodo be tested on? Would it be best to test it on mice?
Mice would be the best option to test L-DilodoTyrosine. The reason is because Salmonella Typhi causes a similar response in mice that Salmonella Typhimurium causes in humans.
In the previous sections of MCDB you had stated that the results were promising. Why were the results promising and why were they successful?
In previous sections of MCBD, L-Diiodo Tyrosine was found be be a “hit” over 6 different times.
What properties do stronger antibiotics have that give them the potential to be useful in slowing the spread of antibiotic resistant bacteria?
Stronger antibiotics are more aggressive towards the bacteria. Therefore the bacteria would have to have a very high resistance to that antibiotic. The best way to visualize this is with the video Aiden played in her presentation.