Hi Thomas, thank you for your question! One way of categorizing bacteria would be based on their cell membrane. If the layer of peptidoglycan on their membrane is thick, this means the bacteria is gram positive, if it is thin, it is gram negative. Salmonella Typhimurium is gram negative, so the compound can penetrate the bacteria easier. I would imagine that all gram negative bacteria would show a similar effect when exposed to Bromelain.
Could you elaborate on your future directions related to the hit doses on somatic cells and what it would confirm or show that Bromelain is doing at this level?
Hi Morgan, performing a dose response protocol on somatic cells would reveal the effect that Bromelain has on actual human cells. For this research we were only able to see the effect it had on Salmonella Typhimurium, which is a much smaller model organism.
Hi Niki, I don’t believe we can standardize the dosages, it depends on the compound and organism what dose is effective, which is why we perform dose response protocols.
Is there a way of categorizing bacteria so that you could potentially narrow down which types or groups bromelain is potentially capable of infecting?
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Hi Thomas, thank you for your question! One way of categorizing bacteria would be based on their cell membrane. If the layer of peptidoglycan on their membrane is thick, this means the bacteria is gram positive, if it is thin, it is gram negative. Salmonella Typhimurium is gram negative, so the compound can penetrate the bacteria easier. I would imagine that all gram negative bacteria would show a similar effect when exposed to Bromelain.
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Could you elaborate on your future directions related to the hit doses on somatic cells and what it would confirm or show that Bromelain is doing at this level?
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Hi Morgan, performing a dose response protocol on somatic cells would reveal the effect that Bromelain has on actual human cells. For this research we were only able to see the effect it had on Salmonella Typhimurium, which is a much smaller model organism.
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This compound seems like the_bomb.com… What made you chose it?
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Hi Delwin, it really is:) We chose the compound because of its easy accessibility and its homeopathic properties.
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If too high or low dosage results in feeding the bacteria, how can we standardize dosages to ensure that it is effective against bacteria?
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Hi Niki, I don’t believe we can standardize the dosages, it depends on the compound and organism what dose is effective, which is why we perform dose response protocols.
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