9 thoughts on “G5 – Whitefield

  1. Nice job! What do you think the potential effects would be if you knocked out the bZIP gene?

    1. Thanks Aidan! I would assume that the tail length would be the same but the infection would not be effective/ not effective at all, or potentially making the phage temperate and not lytic. Without this domain, the phage would have a harder time expressing the viral DNA and repressing the host cell DNA.

    2. Thanks Aidan! I would assume that some effects might be the effectiveness of infection, I assume that the tail length would stay the same but the tail might not be functional.

  2. That was a great presentation and I really appreciated your background section. One thing I’d like to ask: How is this research being used to benefit the scientific community? In other words, what problem does this research aim to solve?

    1. Hi Savannah! This research can help with better analyzing bacteriophage genomes for the use to phage therapy, this analysis would allow us to understand what genes are crucial for infection and how genes could potentially be modified to be the most effective.

    1. Hi Abbey! Great question, the importance of the bacteriophage tail is that it is how a phage infects a host cell, the tail has all the machinery to detect the host cell and insert it’s DNA into a host cell. Without the bacteriophage tail, a phage would not be able to infect bacterial cells.

  3. How does the bacteriophage tail change affect the the phage when interacting with a host cell?

    1. Great question Grace! The tail itself doesn’t have a particular structure change other than attaching to the host cell and inserting it’s DNA into the host cell.

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